Acute Care Nurse Practitioner Mayo Clinic Florida Jacksonville, Florida
Disclosure(s): No relevant financial relationship(s) to disclose.
Disclosure(s):
Diane C. McLaughlin, AGACNP-BC, DNP, FCCM: No relevant financial relationship(s) to disclose.
Data support the theory, that in brain death, malfunction of the hypothalamic-pituitary-adrenal axis results in low levels of cortisol and thyroid hormones that can contribute to hypotension and subsequent organ deterioration. The administration of exogenous hormones has been found to increase hemodynamic stability, decrease requirements for vasoactive therapy, and increase the total numbers of organs transplanted. Patients may develop either diabetes insipidus (DI) or Syndrome of inappropriate antidiuretic hormone (SIASH) or switch between the 2. In addition corticosteroid use may lead to hyperglycemia which may be managed with an insulin infusion. Pharmacotherapy of these complications will be discussed. In addition, the change in viable organs in patients who develop DI or SIADH will be described
Presentations in this session: Avoiding engine trouble - thyroid regulation and management - Dimitrios A. Savva, PharmD, BCPPS Keeping up the pressure - Steroid Management - Michael Agus, MD, FCCM Not Too Sweet or Salty: Glucose and Sodium Homeostasis - Diane C. McLaughlin, DNP, AGACNP-BC, CCR
